Anti-Phospho-ERK 3 (S189) antibody
504.6 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 665 - STJ90898
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 200 µl
A03011S189-1
Anti-Phospho-ERK 3 (S189) MAPK6 Antibody
Boster Bio Anti-Phospho-ERK 3 (S189) MAPK6 Antibody catalog # A03011S189-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
720 €
STJ90260
Anti-Phospho-ERK 1/2 (T202) antibody
ERK 1/2 is a protein encoded by the MAPK1 gene which is approximately 41,4 kDa. ERK 1/2 is localised to the cytoplasm and nucleus. It is involved in RET signalling, activated TLR4 signalling, IL-2 pathway, regulation of lipid metabolism and insulin signalling-generic cascades. This protein falls under the MAP kinase family. It is a serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. It also acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. ERK 1/2 is expressed in the nervous system, blood, lung, liver and skin. Mutations in the MAPK1 gene may result in small intestine neuroendocrine neoplasm and pertussis. STJ90260 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous ERK 1/2 protein which only binds about T202 when T202 is phosphorylated.
504.6 €
STJ22263
Anti-Phospho-MAPK6-(S189) antibody
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
857.4 €
STJ110863
Anti-Phospho-ERBB2-(Y1221/1222) antibody
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
857.4 €
A00296Y1284-1
Anti-Phospho-ErbB-4 (Y1284) Antibody
Boster Bio Anti-Phospho-ErbB-4 (Y1284) Antibody catalog # A00296Y1284-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
720 €
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