![ORAI1 Antibody [3F6H5]](/images/no-image-product-box.jpg "ORAI1 Antibody [3F6H5]")
ORAI1 Antibody [3F6H5]
439.27 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 223 - PM-5205-002mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 0.02 mg
Parameters
| Additional information | Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
|---|---|
| Storage and shipping | ORAI1 monoclonal antibody can be stored at -20˚C, stable for one year. |
PM-5205-002mg
ORAI1 Antibody [3F6H5]
ORAI1 Monoclonal Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI1 is a recently identified four-transmembrane spanning protein that is an essential component of CRAC. A missense mutation in this protein in humans is the cause of one fo rm of hereditary severe combined immune deficiency (SCID) which results in ablated T-cell Ca++ entry. It has been suggested that ORAI1 functions as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. ORAI1 often migrates at a higher than expected molecular weight in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ORAI2 or ORAI3.
439.27 €
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