RecombinantMCP-1/CCL2,Human
4110 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 965 - BK0125
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 1mg
Parameters
| Additional information | Chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemotactic protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Human CCL2 cDNA encodes a 99 amino acid (aa) precursor protein with a 23 aa signal peptide and a 76 aa mature protein. Human CCL2 shares 78-79% aa identity with canine, porcine and equine CCL2, while mouse and rat express a form of CCL2 that is extended by 49 aa and shares only ~56% aa identity within the common region.Recombinant Human MCP-1/CCL2 produced in E.coli is a single non-glycosylated polypeptide chain containing 76 amino acids. A fully biologically active molecule, rhMCP-1/CCL2 has a molecular mass of 8.7 kD analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript. |
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BK0321
RecombinantMCP-1/CCL2,Rat
The EC50 value of rat MCP-1/CCL2 on Caˆ2+ mobilization assay in CHO-K1/G15/rCCR2 cells (human G15 and rat CCR2 stably expressed in CHO-K1 cells) is less than 0.3 μg/ml.
453 €
BK0321
RecombinantMCP-1/CCL2,Rat
The EC50 value of rat MCP-1/CCL2 on Caˆ2+ mobilization assay in CHO-K1/G15/rCCR2 cells (human G15 and rat CCR2 stably expressed in CHO-K1 cells) is less than 0.3 μg/ml.
420 €
BK0125
RecombinantMCP-1/CCL2,Human
The EC50 value of human MCP-1/CCL2on Caˆ2+ mobilization assay in CHO-K1/Gα15/hCCR2 cells (human Gα15 and human CCR2 stably expressed in CHO-K1 cells) is less than 1μg /ml.
4110 €
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