ABT 737-d8

HY-50907S

ABT-737-d8

ABT 737-d8 is the deuterium labeled ABT-737. ABT-737, a BH3 mimetic, is a potent Bcl-2, Bcl-xL and Bcl-w inhibitor with EC50s of 30.3 nM, 78.7 nM, and 197.8 nM, respectively. ABT-737 induces the disruption of the BCL-2/BAX complex and BAK-dependent but BIM-independent activation of the intrinsic apoptotic pathway. ABT-737 induces autophagy and has the potential for acute myeloid leukemia (AML) research[1][2][3].

2467.64 €

MBS6057143-1mg

ABT 737-d8

956.38 €

MBS6057143-5x1mg

ABT 737-d8

3455.38 €

A112550

ABT 737

852808-04-9

445.5 €

MBS6030015-5mg

ABT 737

771.5 €

MBS6030015-5x5mg

ABT 737

2639.38 €