ELISA kit for Human Leukemia-associated protein 7 (DLEU7)

ELISA kit for Human Leukemia-associated protein 7 (DLEU7)

3987 EUR

3987 EUR
In Stock
quantity
Produktdetaljer

Katalognummer: 749 - KTE62031-5platesof96wells

Produktkategori: Företag och industri > Vetenskap och laboratorium

Leverantör:

AbbkineGentaur

Storlek: 5 plates of 96 wells

Parameters

Additional informationDeletion of chromosome 13q14 is the most frequent genetic aberration in B-cell chronic lymphocytic leukemia (CLL), found in more than 50% of cases, indicating that this region contains a gene(s) involved in the development of CLL.DLEU7, located adjacent to the consensus deleted region, and overlapping the 3' end of DLEU1 tail to tail. Human DLEU7 encodes a putative 221 amino acid protein, with significant conservation in rodents. Mutational and expression analysis in primary CLL samples failed to demonstrate any specific mutations in DLEU7, but no DLEU7 expression could be detected in CLL cells. Methylation of a CpG island in the promoter region of DLEU7 was further analyzed as a possible mechanism for the absence of DLEU7 expression, and the promoter was found to be methylated in the majority of the CLL samples investigated.
Storage and shippingAll of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).