SimMet

SM1

SimMet

21948 €

SM1-AM

SimMet Annual Maintenance

5209.8 €

HY-115552

Simmiparib

Simmiparib is a highly potent and orally active PARP1 and PARP2 inhibitor with IC50 values of 1.75 nM and 0.22 nM, respectively. Simmiparib has more potent PARP1/2 inhibition than its parent Olaparib (HY-10162). Simmiparib induces DNA double-strand breaks (DSB) accumulation and G2/M arrest in homologous recombination repair (HR)-deficient cells, thereby inducing apoptosis. Simmiparib exhibits remarkable anticancer activities in cells and nude mice bearing xenografts[1].

2272.83 €

LS006492

SIM1 (NM_005068) Human Over-expression Lysate

Transient overexpression lysate of single-minded homolog 1 (Drosophila) (SIM1)

1590 €

LS006493

SIM2 (NM_009586) Human Over-expression Lysate

Transient overexpression lysate of single-minded homolog 2 (Drosophila) (SIM2), transcript variant SIM2s

1590 €

E45H07508-2

SIM1 (NM_005068) Human Over-expression Lysate

742.5 €